- CHAPTER 1
Frame of Reference
- CHAPTER 3
What Is Cancer?
- CHAPTER 5
Where It Starts
- CHAPTER 6
How It Spreads
- CHAPTER 7
Why Its Harmful
- CHAPTER 8
Clue to the Cause
- CHAPTER 9
Every 20 Seconds...
- CHAPTER 10
Survival Rates Today
- CHAPTER 11
Long-Term Trends
- CHAPTER 13
Specialized Medical Centers
- CHAPTER 14
The "Societies"
- CHAPTER 15
Big Pharma
- CHAPTER 16
"Smart Bombs"
- CHAPTER 17
Treatment Choices
- CHAPTER 18
Clinical Trials
- CHAPTER 19
Surgery
- CHAPTER 20
How Chemo Works
- CHAPTER 21
Side Effects
- CHAPTER 22
Damaged Atoms
- CHAPTER 23
Radiation Therapy
- CHAPTER 24
Monoclonal Antibodies
- CHAPTER 25
"Big 3" Blockbuster Drugs
- CHAPTER 26
Drugs from Small Molecules
- CHAPTER 27
Types of Coverage
- CHAPTER 28
Underinsured
- CHAPTER 29
Uninsured
- CHAPTER 30
Patient Empowerment
- CHAPTER 35
It’s Getting Expensive
- See, the Jonathan Alter article in the 4/29/07 issue of
Newsweek magazine.
- See, www.biooncology.com
- See, the book entitled "Genome – the Autobiography of a
Species in 23 Chapters" (Harper Books 2000); see also, the
"FAQs" section at www.cancergenome.nih.gov
The analogy that 100 trillion dimes would fill the Empire State
Building comes from a UK-based website dedicated to explaining
cell biology to children (www.cellsrus.uk)
- See, the article "Hallmarks of Cancer," by D Hanahan and RA
Windberg, in the 1/7/00 issue of Cell magazine; for PET-scan
images of metastatic cancer, see www.uams.edu/radiology;
for a discussion of "staging," see, www.breastcancer.org.
- This chapter draws upon three of the most comprehensive
websites concerning cancer: and they are www.cancer.gov,
www.cancer.org and www.cancer.net (collectively
sometimes referred to as the "Master Websites."); see also
www.meb.uni-bonn.de-cancer.gov/media.
- See, the book Genes and Disease: which can be found on
the Internet at www.ncbi.nlm.nih.gov.
- See, 4/8/07 and 7/29/07 issues of the New York Times
with articles on the most serious diseases affecting Americans.
- See, 8/7/07 issue of the New York Times (at page F6); see
also SEER data on 2006 cancer cases available from the
American Cancer Society ("ACS").
- See, ACS website for survival rate data; see also,
www.lungcanceralliance.org
- For all major oncology centers within the NCCN network,
websites provide statistics on the number of clinical trials
each of them is conducting, segmented by cancer type; that
is the source of the clinical trials data presented here. (which
is as of 2007)
- See, websites of each of the organizations mentioned for
basic data about them (such as annual budget and
membership).
- See, the article "Big Pharma Faces Grim Prognosis" in the
12/6/2007 edition of the Wall Street Journal. See also,
the article entitled "Beyond Fast Track For Drug Approvals" in
the 7/24/07 edition New England Journal of Medicine.
- The author coined the phrase "smart bombs." The diagram
in this chapter is original and depicts different branches of
cancer-killing drugs.
- See, the Master Websites.
- See, the Master Websites.
- For a synopsis of the different cancer-related surgeries,
see, (www.cancer.org).
- The author coined the phrase "carpet-bombing" and the
diagram is original; for discussion of the many aspects of
chemotherapy, see, the Master Websites.
- The information in this chart derives primarily from the Master
Websites.
- See, www.radiologyinfo.org.
- See, the "FAQ Sheet" about radiation therapy on the NCI’s
website (www.cancer.gov).
- See, www.gene.com; see, also, the article entitled "Gaining
Ground on Breast Cancer" in the June 2008 issue of Scientific
America and the article entitled "It’s a Mab Mab World,"
appearing in the 5/21/07 issue of The Deal magazine.
- Most of this data is drawn from Genentech’s excellent
and informative website (www.gene.com)
- See, "Small Molecules, Big Player" an article appearing in
the 9/15/06 issue of the Journal Cancer Research which is
published by the AACR and is available on their website
(aacrjournals.org).
- The NCI annually published its "Cancer Facts and Figures"
and in 2008 included a special section entitled "Insurance
and Cost-Related Barrier to Cancer Care," which provided
the basis for much of the information in this chapter.
- See, The Managed Care Answer Guide, which can be found at
www.patientadvocate.org
- See, the pamphlet Medicaid At-a-Glance, available from the
U.S. Dept. of Health and Human Services. See also,
www.wvhealthright.org.
- See, The Wise Patient’s Guide to Being and Empowered
Patient, which may be found at www.patients.about.com.
- See, the 2/12/2008 edition of USA Today.
For the approximate estimated cost of a year’s worth of
some of the new anti-cancer drugs, see the article "Cancer
Cures and Blockbuster Drugs," by GLG Mkilos, PhD and PJ
Baird, PhD, in "Dean’s World" website.
For the percentages of "who pays" for cancer treatment
annually, see "How the Nation’s Health Dollar is Spent," in the
Winter 2006 issue of Cure magazine.